Poor sleep linked to dementia and early death, study finds
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“These results contribute to existing knowledge that sleep plays a very important role, each and every night, for reducing our longer term risk for neural cognitive decline and all cause mortality,” said study author Rebecca Robbins, an instructor in medicine at Harvard Medical School who specializes in sleep research.
In addition, 50 million to 70 million Americans struggle with sleep disorders such as sleep apnea, insomnia and restless leg syndrome, which can ruin a good night’s shuteye.
The CDC calls that a “public health problem,” because disrupted sleep is associated with a higher risk of conditions including diabetes, stroke, cardiovascular disease — and dementia.
Highest risks
Data from between 2011 and 2018 were examined for the new study, with a focus on people in the highest risk category — those who said they had sleep issues “most nights or almost every night.”
Self-reported sleep difficulties by participants in the study were then compared to each participant’s medical records.
Because the NHATS study collected annual sleep data, the new study was able to follow the totality of sleep difficulties for each person over the entire eight years, instead of just capturing a snapshot in time. This was a strength of the study, Robbins said, because “sleep health can ebb and flow over the years.”
Another strength of the study was the ability to tease apart the impact of having a good bit of trouble falling asleep versus frequent nighttime awakenings on any risk of dementia and death.
“We found a strong association between frequent difficulty falling asleep and nighttime awakenings and dementia and early death from any cause, even after we controlled for things like depression, sex, income, education and chronic conditions,” Robbins said.
People who had trouble falling asleep most nights had about a 44% increased risk of an early death from any cause, the study found. Those who said they often woke in the night and struggled to return to sleep had a somewhat higher risk — a 56% increased risk of early death from any cause.
The risk for dementia was similar: People who reported routinely experiencing difficulty falling asleep had a 49% increased risk of dementia, while those who often woke in the night and had difficulty falling back asleep had a 39% increased risk of dementia.
But it was the people who had a lot of problems falling and staying asleep that had the highest risk of either dementia or dying early from any cause.
“We found a 56% increased risk of dementia and an 80% greater risk of all cause mortality over the following eight years among those who experienced both concurrent sleep difficulties — falling asleep or waking from sleep,” Robbins said.
Additional studies
High quality sleep is critical to our overall health, and cognitive reserve, experts say.
A week of disrupted sleep increased the amount of tau, another protein responsible for the tangles associated with Alzheimer’s, frontal lobe dementia and Lewy body disease, the study found.
In addition, persistent short sleep duration between the ages of 50, 60 and 70 was also associated with a “30% increased dementia risk,” independent of “sociodemographic, behavioural, cardiometabolic, and mental health factors,” including depression, the study said.
What to do?
Medical science has no current cure for dementia, but there are things you can do to reduce your risk.
Stop smoking, drink only in moderation — if you drink at all — eat a well balanced diet, exercise, stay mentally active and keep your blood pressure and cholesterol levels in check are excellent ways to keep brains and bodies healthy, experts say.
Other tips include having a comfortable bed and pillow, keeping the bedroom cool, quiet and dark and avoiding caffeine and alcohol for hours before bed.
Whatever you do, don’t stay sleep deprived: If you try these tips and can’t seem to relax, or your sleep continues to worsen, be sure to reach out to your doctor or a sleep health professional.
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